PLoS ONE (Jan 2020)

Attention-deficit/hyperactivity disorder and smoking habits in pregnant women.

  • Anneli Andersson,
  • Tor-Arne Hegvik,
  • Qi Chen,
  • Mina A Rosenqvist,
  • Liv Grimstvedt Kvalvik,
  • Catarina Almqvist,
  • Brian M D'Onofrio,
  • Catharina Hartman,
  • Kari Klungsøyr,
  • Jan Haavik,
  • Catherine Tuvblad,
  • Henrik Larsson

DOI
https://doi.org/10.1371/journal.pone.0234561
Journal volume & issue
Vol. 15, no. 6
p. e0234561

Abstract

Read online

BackgroundAttention-deficit/hyperactivity disorder (ADHD) has been associated with an increased risk of tobacco smoking, and more difficulties with smoking cessation compared to non-ADHD individuals. Women with ADHD may therefore show elevated rates of smoking during pregnancy.AimsTo examine the association between ADHD and smoking habits among pregnant women in Sweden and Norway.MethodsWomen pregnant for the first time were identified in Sweden (n = 622,037), and Norway (n = 293,383), of which 1.2% (n = 7,444), and 1.7% (n = 4,951) were defined as having ADHD, respectively. Data on smoking habits were collected early and late in pregnancy.ResultsIn Sweden, ADHD was associated with an increased risk of smoking early in pregnancy, adjusted risk ratio (adjRR) 2.69 (95% confidence interval, 2.58-2.81), and late in pregnancy, adjRR 2.95 (2.80-3.10). Similar findings were observed in the Norwegian data, early in pregnancy, adjRR 2.31 (2.21-2.40), and late in pregnancy, adjRR 2.56 (2.42-2.70). Women with ADHD were more likely to continue smoking during pregnancy, compared to women without ADHD, both in Sweden adjRR 1.13 (1.10-1.17), and in Norway, adjRR 1.16 (1.12-1.20). Having a sibling diagnosed with ADHD was associated with an increased risk of smoking early and late in pregnancy, in both Sweden and Norway.ConclusionsWomen with ADHD are considerably more likely to smoke early and late in (their first) pregnancy and are less likely to stop smoking between the two time points. Smoking, early and late in pregnancy, co-aggregates in families with ADHD. Smoking prevention and intervention programs should be targeted towards women with ADHD, specifically during their childbearing years, to ensure better mother and child outcomes.