Olfactory bulb acetylcholine release dishabituates odor responses and reinstates odor investigation

M. Cameron Ogg; Jordan M. Ross; Mounir Bendahmane; Max L. Fletcher

doi:10.1038/s41467-018-04371-w

Nature Communications (May 2018)

Olfactory bulb acetylcholine release dishabituates odor responses and reinstates odor investigation

M. Cameron Ogg,
Jordan M. Ross,
Mounir Bendahmane,
Max L. Fletcher

Affiliations

M. Cameron Ogg: Department of Anatomy and Neurobiology, University of Tennessee Health Science Center
Jordan M. Ross: Department of Anatomy and Neurobiology, University of Tennessee Health Science Center
Mounir Bendahmane: Department of Anatomy and Neurobiology, University of Tennessee Health Science Center
Max L. Fletcher: Department of Anatomy and Neurobiology, University of Tennessee Health Science Center

DOI: https://doi.org/10.1038/s41467-018-04371-w
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 11

Abstract

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Habituation reduces neural responsiveness to prolonged irrelevant stimuli and dishabituation reverses these effects when a salient stimulus is encountered. Here the authors demonstrate that acetylcholine is involved in dishabituating odor responses in the mouse olfactory bulb.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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