Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia

Abstract

The data of the comparative analysis of separate parameters of cell and humoral chains of immune response in patients suffering from pulmonary tuberculosis accompanied by eosinophilia has been presented in the article.With involving contemporary immunological methods of research, it has been stated that tuberculosis infection in combination with eosinophilic blood reaction is accompanied by marked cytokine imbalance, characterized by increase in the concentration of IL-5 (mediator with anti-inflammatory activity) in blood serum against the background of low serum level of the key anti-tuberculosis cytokine — IFN-γ.

Keywords

• туберкулез легких
• эозинофилы
• лимфоциты
• цитокины