Journal of Veterinary Research (Jun 2024)
Effect of β-hydroxybutyrate acid on gene expression levels of antioxidant biomarkers and growth hormone–related genes in liver cell culture
- Mohsin Muhammad Ali,
- Zhou Xiaojing,
- Huiru Yu,
- Shen Wenxiang,
- He Baoxiang,
- Sobiech Przemysław,
- Pierzchała Mariusz,
- Ogłuszka Magdalena,
- Starzyński Rafał,
- Kalra Garima,
- Deshmukh Bharti,
- Thangarasu Revathy,
- Kashyap Neeraj,
- Czarnik Urszula,
- Lepczyński Adam,
- Woźniakowski Grzegorz,
- Pareek Chandra S.
Affiliations
- Mohsin Muhammad Ali
- 1Department of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, China
- Zhou Xiaojing
- 1Department of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, China
- Huiru Yu
- 1Department of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, China
- Shen Wenxiang
- 1Department of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, China
- He Baoxiang
- 1Department of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, China
- Sobiech Przemysław
- 3Department of Clinical Sciences, Internal Disease Unit, Faculty of Veterinary Medicine, Utrecht, Netherlands
- Pierzchała Mariusz
- 5Department of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552Magdalenka, Poland
- Ogłuszka Magdalena
- 5Department of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552Magdalenka, Poland
- Starzyński Rafał
- 5Department of Genomics and Biodiversity, Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, 05-552Magdalenka, Poland
- Kalra Garima
- 6Department of Animal Genetics and Breeding, Ludhiana, Punjab, India
- Deshmukh Bharti
- 6Department of Animal Genetics and Breeding, Ludhiana, Punjab, India
- Thangarasu Revathy
- 7College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, 141004, Punjab, India
- Kashyap Neeraj
- 7College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, 141004, Punjab, India
- Czarnik Urszula
- 4Department of Pig Breeding, Faculty of Animal Bio-Engineering, University of Warmia and Mazury in Olsztyn, 10-719Olsztyn, Poland
- Lepczyński Adam
- 8Department of Physiology, Cytobiology and Proteomics, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology, 71-270Szczecin, Poland
- Woźniakowski Grzegorz
- 9Department of Infectious and Invasive Diseases and Veterinary Administration, Institute of Veterinary Medicine, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 87-100Toruń, Poland
- Pareek Chandra S.
- 9Department of Infectious and Invasive Diseases and Veterinary Administration, Institute of Veterinary Medicine, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 87-100Toruń, Poland
- DOI
- https://doi.org/10.2478/jvetres-2024-0037
- Journal volume & issue
-
Vol. 68,
no. 2
pp. 313 – 324
Abstract
In dairy cattle, oxidative stress is a predominant problem associated with diseases and reproductive health issues. This study aimed to detect the variation in the antioxidant biomarkers by adding different concentrations of β-hydroxybutyric acid (BHBA) and sought to elucidate its effects on the gene expression levels of growth hormone (GH) and antioxidant biomarkers in bovine hepatocytes.
Keywords
