Сахарный диабет (Dec 2022)

Diabetes mellitus type 1 and coronary artery disease with severe systolic heart failure in 25 year-old adult

  • A. A. Voznesenskaya,
  • I. Z. Bondarenko,
  • K. V. Melkozerov,
  • R. S. Kosharnaya,
  • A. S. Zakharov,
  • M. Yu. Movsesyants,
  • M. D. Kuklina,
  • V. Yu. Kalashnikov

DOI
https://doi.org/10.14341/DM12865
Journal volume & issue
Vol. 25, no. 5
pp. 514 – 521

Abstract

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Diabetes mellitus (DM) type 1 accounts for up to 90% of all cases of diabetes among children, adolescents and young adults (10 % are represented by T2DM, MODY, etc.). DM is characterized not only by glucose metabolism disorder, but also by abnormal protein and lipid metabolism, leading to severe macrovascular complications. A clinical case of diabetes type 1, hyperlipidemia, coronary artery disease (CAD) and chronic heart failure (HF) in a 25-year-old adult has been demonstrated. The medical examination revealed lipid metabolism disorders, multivessel coronary artery disease, which required myocardial revascularization, and severe heart failure with a reduced ejection fraction (HFrEF). The clinical case demonstrates that proper cardiovascular examination should be performed in all patients with diabetes and lipid disorders, regardless of age and type of diabetes. The authors also consider the use of sodium-glucose

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