Antibacterial Effect of Latex and Aqueous and Hydroalcoholic Extracts of Sonchus Oleraceus L.

Abstract

Background and Objectives: Appearance of multidrug-resistant bacteria has created significant clinical problems in treatment of infectious diseases. Sonchus oleraceus plant with many medicinal properties can be a potential source of antibacterial effects. Methods: Aqueous and hydroalcoholic extracts of S. oleraceus were prepared by maceration and antibacterial effect of these extracts as well as latex on Escherichia coli and Staphylococcus aureus were investigated by micro broth dilution method and MIC/ MBC according to CLSI. Results: Minimum lethal concentrations in latex and aqueous and hydroalcoholic extracts for E. coli respectively 7.8, 15.6 and 7.8 mg / ml and for S. aureus, respectively. 3.9, 7.8 and 62.5 mg / ml were obtained. The highest antibacterial effect was observed in plant latex on S. aureus according to the diameter of inhibition zone. Conclusion: This study presents the first results of the antibacterial effects of latex and aqueous and hydroalcoholic extracts of S. oleraceus in Iran. The highest inhibitory effect was related to latex at 3.9 mg / ml on S. aureus. Further studies can help us understand the antimicrobial potential of this plant.

Keywords

• sonchus oleraceus
• latex
• aqueous extract
• hydroalcoholic extract
• staphylococcus aureus
• escherichia coli