Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review

Abstract

In this review, the authors briefly examine the most recent evidence concerning the role of several proteins involved in tubular urate transport. They also analyse the influence of extracellular volume, electrolyte disorders, acid-base imbalance, and insulin-resistance on renal clearance of uric acid.

Keywords

• tubular handling
• urate clearance
• urate transport
• Uric acid