763 Intratumoral delivery of high potency STING agonists modulates the immunosuppressive myeloid compartment and induces curative responses in checkpoint-refractory glioblastoma models

• Michael Curran,
• Chao-Hsien Chen,
• Rodney Cheng-En Hsieh,
• Genevieve Hartley,
• Spencer Lea

Affiliations

Michael Curran

Aff1 grid.240145.60000000122914776Department of ImmunologyUniversity of Texas MD Anderson Cancer Center Houston TX USA

Chao-Hsien Chen

Aff1 0000 0001 2291 4776grid.240145.6Department of ImmunologyUniversity of Texas MD Anderson Cancer Center U902 7455 Fannin St 77054 Houston TX USA

Rodney Cheng-En Hsieh

1The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Genevieve Hartley

1The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Spencer Lea

1The University of Texas MD Anderson Cancer Center, Houston, TX, USA