Comparative study between multi-detector CT angiography and digital subtraction angiography in evaluation of peripheral arterial occlusive disease

Abstract

Objective: The aims of the study were the evaluation of peripheral arterial occlusive disease with multidetector or multi-slice CT angiography (MDCTA) and comparison of the results with the results of digital subtraction angiography (DSA), a standard reference. Patients and method: The written informed consent of the patients and ethics committee approval were obtained. The prospective study group consisted of 10 patients complaining of peripheral arterial disease. Using MDCT-A, the arterial tree of the lower extremity was evaluated for the presence of steno-occlusive lesions that might have led to luminal stenosis. The diagnostic accuracy of MDCTA was calculated and compared with that of DSA. Results: In the segment-based analysis, the sensitivity, specificity, and accuracy of MDCT angiography in determining significant stenoses were 100%, 99.3%, and 99.6.3%, respectively. The compatibility between MDCTA and DSA methods in grading stenosis was calculated as 0.896 (P < 0.007) and it was statistically significant. Conclusion: MDCT angiography is significantly compatible with DSA method in the evaluation of peripheral arterial diseases. It is a non-invasive method and can be an alternative to DSA.

Keywords

• Lower extremity arteries
• Peripheral arterial disease
• Multi-detector computer tomography
• Digital subtraction angiography