Journal of Immunotherapy and Precision Oncology (Feb 2022)
Selinexor in Combination with Carboplatin and Pemetrexed in Patients with Advanced or Metastatic Solid Tumors: Results of an Open-Label, Single-Center, Multi-Arm Phase 1b Study
- Kyaw Z. Thein,
- Siqing Fu,
- Filip Janku,
- Apostolia M. Tsimberidou,
- Sarina A. Piha-Paul,
- Daniel D. Karp,
- Jatin Shah,
- Denái R. Milton,
- Jing Gong,
- Selma Sulovic,
- Lacey McQuinn,
- Bettzy A. Stephen,
- Rivka R. Colen,
- Brett W. Carter,
- Funda Meric-Bernstam,
- Aung Naing
Affiliations
- Kyaw Z. Thein
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Siqing Fu
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Filip Janku
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Apostolia M. Tsimberidou
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Sarina A. Piha-Paul
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Daniel D. Karp
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Jatin Shah
- 3 Karyopharm Therapeutics, Newton, MA, USA
- Denái R. Milton
- 4 Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Jing Gong
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Selma Sulovic
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Lacey McQuinn
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Bettzy A. Stephen
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Rivka R. Colen
- 5 Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Brett W. Carter
- 6 Department of Thoracic Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Funda Meric-Bernstam
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
- Aung Naing
- 1 Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Abstract
No abstracts available.Keywords
- selinexor
- carboplatin
- pemetrexed
- metastatic solid tumors
- selective inhibitor of nuclear export (sine)