The Positive Effects of Physical Activity on Quality of Life in Parkinson’s Disease: A Systematic Review

Abstract

Background: Physical activity can have positive effects on motor and non-motor symptoms in Parkinson’s disease, but its benefits in terms of quality of life and function are uncertain and vary based on the specific forms of activities and interventions. Objective: We sought to assess the current evidence on the positive effects of physical activity in people with Parkinson’s disease and more specifically in relation to its potential benefits for quality of life. Methods: This systematic review was conducted between January and April 2024 via the PubMed, Medline, and Scopus databases. Predetermined search criteria were used that included the following terms: “Parkinson’s disease”, “quality of life” and “physical activity”. Results: A total of 1669 articles were identified. After utilizing predetermined criteria, a total of fifteen articles met the selection criteria. Statistically significant improvements in quality of life were found in seven studies. Seven studies demonstrated a significant improvement in non-motor symptoms, while nine studies showed an improvement in motor symptoms. Conclusions: Despite heterogeneity in the study designs, interventions and clinical assessments, the articles identified in this review yielded mostly positive results in relation to physical activities. The findings reflect an improvement in motor and non-motor symptoms may translate to a better quality of life in people with Parkinson’s disease.

Keywords

• Parkinson’s disease
• neurodegenerative diseases
• exercise
• physical activity
• quality of life