Present Situation of Lung Cancer Screening Methods

Abstract

Lung cancer is the leading cause of cancer mortality currently. Early diagnosis is crucial to the good prognosis of lung cancer. Evidence has shown that low-dose computed tomography (CT) screening can make the decline in the mortality of lung cancer. However, there are still many problems in the screening, such as, high false-positive rates, overdiagnosis and radiation exposure. As another non-invasive tumor screening method, blood-based tumor markers showed a high sensitivity and specificity in early diagnosis of lung cancer in recent years. How to establish a comprehensive mode for lung cancer screening by use existing screening methods, we need more clinical research.

Keywords

• Lung neoplasms
• Screening
• Low-dose computed tomography
• Circulating tumor cells
• Autoantibodies