Identification of Fusarium verticillioides using gene sequencing in a patient after orthotopic liver transplantation

Abstract

Fusarium is an opportunistic fungal pathogen which is emerging as a significant cause of morbidity and mortality particularly in patients with haematological malignancies and bone marrow transplant recipients but also in solid organ transplant recipients. Here we have diagnosed a case of disseminated Fusarium infection with cutaneous localization in a patient undergoing a second liver transplant after chronic rejection of primary graft. The morphology of the isolated strain didn’t allow a clear distinction between Fusarium. napiforme and Fusarium. verticillioides. For this reason it was performed a gene sequencing analysis to have a reliable identification.The isolated strain was thus identified as F. verticillioides.

Keywords

• Fusarium verticillioides, gene Gene sequencing, ?-Tubulin, translation Translation elongation factor EF-1