Frontiers in Pediatrics (Nov 2024)

Effectiveness of pre-Omicron COVID-19 mRNA vaccines against hospitalizations in infection-naïve children: a case-control study

  • Lung Chang,
  • Lung Chang,
  • Ching-Ying Huang,
  • Ching-Ying Huang,
  • Nan-Chang Chiu,
  • Nan-Chang Chiu,
  • Jin-Yuan Wang,
  • Hsin Chi,
  • Hsin Chi,
  • Tsung-Ning Daniel Huang,
  • Tsung-Ning Daniel Huang

DOI
https://doi.org/10.3389/fped.2024.1387086
Journal volume & issue
Vol. 12

Abstract

Read online

This case–control study spanned from July 2022 to September 2023, focusing on the pre-Omicron COVID-19 mRNA vaccine effectiveness against the Omicron variant in children without prior SARS-CoV-2 exposure. We reported that pre-Omicron COVID-19 mRNA vaccines significantly reduced Omicron-induced hospitalizations in infection-naïve Taiwanese children. Our study also highlighted the socioeconomic factors influencing COVID-19 vulnerability among the children population.

Keywords