Frontiers in Pediatrics (Nov 2024)
Effectiveness of pre-Omicron COVID-19 mRNA vaccines against hospitalizations in infection-naïve children: a case-control study
Abstract
This case–control study spanned from July 2022 to September 2023, focusing on the pre-Omicron COVID-19 mRNA vaccine effectiveness against the Omicron variant in children without prior SARS-CoV-2 exposure. We reported that pre-Omicron COVID-19 mRNA vaccines significantly reduced Omicron-induced hospitalizations in infection-naïve Taiwanese children. Our study also highlighted the socioeconomic factors influencing COVID-19 vulnerability among the children population.
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