Cytokines Torment associated to COVID-19

Abstract

Introduction:COVID-19 is the disease caused by a new coronavirus SARS-CoV-2 that was identified and characterized in January 2020 in China. This condition is accompanied by an aggressive inflammatory response with a huge liberation of pro-inflammatory cytokines. This event is called cytokines torment. Objective: to describe cytokines torments associated to COVID-19. Methods: a review of 29 bibliographic references was made, consulting articles from Elsevier, SciELO, ClinicalKey,Pubmed and Google Schoolar were reviewed, through different databases. Markers cytokines; coronavirus; infection; coronavirus infections; severe acute respiratory syndrome and epidemiology were used as descriptors. Development: all pathological process begins with defects in the T-cells activity and increasing activity of the macrophages and activation of all the immune system because cytokines torments. This potentially deadly affection is presented in patients with COVID-19. Conclusions:infection for COVID-19 is accompanied by an inflammatory aggressive response with the liberation of a huge amount of proinflammatory cytokines. This is called cytokines torments. This can show up with a variety of symptoms that go from a mild flu to a lifethreading disease.

Keywords

• citocinas
• coronavirus
• infección
• infecciones por coronavirus
• síndrome respiratorio agudo grave
• epidemiología