A case report of Mikulicz’s disease

Abstract

Mikulicz’s disease is a unique condition involving the enlargement of the lacrimal and salivary glands, similar to that observed in Sjogren’s syndrome; however, Mikulicz’s disease is clinically characterized by infrequent autoimmune reactions and responsiveness to glucocorticoid treatment. The ultrasound features of the lacrimal and salivary glands in patients with IgG4-Mikulicz’s disease were characterized by multiple hypoechoic areas of varying sizes within the enlarged glands. IgG4 serum level was also elevated, in contrast to the detection of normal levels in Sjogren’s syndrome. In this article, we intended to illustrate a case of Mikulicz’s disease with clinical and imaging features.

Keywords

• mikulicz’s disease
• lacrimal gland
• salivary gland
• swelling
• case report