Coal is a natural inhomogeneous and discontinuous rock, which is very difficult to obtain repeatability test results through the experiment method.This paper based on discrete element software PFC2D and obtained coal deformation damage control parameters by numerical inversion method, and simulated the deformation and failure process of coal rock under uniaxial compression by software.In terms of comparing the results of numerical simulation and laboratory test, the numerical inversion method is proven a useful method to study deformation and destruction of natural material.The numerical simulation results can provide theoretical and data basis for engineering practices.