Epidemiological investigation on drug resistance of Salmonella isolates from duck breeding farms in Shandong Province and surrounding areas, China

Xinyuan Zhao; Wei Li; Shaopeng Hou; Yanjun Wang; Shuyang Wang; Jing Gao; Ruihua Zhang; Shijin Jiang; Yanli Zhu

Poultry Science (Aug 2022)

Epidemiological investigation on drug resistance of Salmonella isolates from duck breeding farms in Shandong Province and surrounding areas, China

Xinyuan Zhao,
Wei Li,
Shaopeng Hou,
Yanjun Wang,
Shuyang Wang,
Jing Gao,
Ruihua Zhang,
Shijin Jiang,
Yanli Zhu

Affiliations

Xinyuan Zhao: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China
Wei Li: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China
Shaopeng Hou: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China
Yanjun Wang: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China
Shuyang Wang: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China
Jing Gao: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China
Ruihua Zhang: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China
Shijin Jiang: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China
Yanli Zhu: Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian 201718, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian 201718, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian 271018, China; Corresponding author:

Journal volume & issue: Vol. 101, no. 8
p. 101961

Abstract

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ABSTRACT: Duck salmonellosis is a common acute septic infectious disease that spreads rapidly, with serious harm to the duck breeding industry and public health. To date, there are few reports about the epidemiological characteristics of drug resistance in Salmonella from ducks. In this study, an epidemiological investigation was conducted on drug resistance of 110 Salmonella strains isolated from multiple duck farms in Shandong Province and surrounding areas, China. The multidrug-resistant (MDR) rate for 110 Salmonella strains was up to 71.82% (79/110), and 12 types of drug resistance genes were detected in all isolates, including β-lactams, aminoglycosides, tetracycline, macrolides, and quinolones resistance genes. Using the multilocus sequence typing (MLST) based on 7 housekeeping genes, 13 various ST types were identified among all strains, and ST19 (32/110, 29.09%) was the primary type. As the dominant serotypes, S. Kottbus and S. Typhimurium were divided into multiple ST types. A total of 6 kinds of plasmid incompatibility groups were carried in the Salmonella strains, of which IncFIIs (29/110, 26.36%) was most prevalent, and the class I integrons were detected in 78.18% (86/110) of strains. Furthermore, we found that some drug resistance genes, plasmid incompatibility groups, and class I integrons coexist in the same strain. This phenomenon indicates that class I integrons and plasmids are important ways for the spread of drug resistance genes. Therefore, the spread of antibiotic resistance in Salmonella had been facilitated, especially erythromycin (108/110, 98.18%), streptomycin (93/110, 84.54%), and tetracycline (53/110, 48.18%). The above research results broadened ideas and provided directions for the transmission mechanism of Salmonella resistance.

Published in Poultry Science

ISSN: 0032-5791 (Print); 1525-3171 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Agriculture: Animal culture
Website: https://www.journals.elsevier.com/poultry-science

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