Journal of Spectroscopy (Jan 2016)

Enamel Based Composite Layers Deposited on Titanium Substrate with Antifungal Activity

  • S. L. Iconaru,
  • A. M. Prodan,
  • C. S. Turculet,
  • M. Beuran,
  • R. V. Ghita,
  • A. Costescu,
  • A. Groza,
  • M. C. Chifiriuc,
  • P. Chapon,
  • S. Gaiaschi,
  • R. Hristu,
  • G. A. Stanciu,
  • R. Trusca,
  • M. Ganciu,
  • S. M. Raita,
  • N. Vineticu,
  • C. S. Ciobanu

DOI
https://doi.org/10.1155/2016/4361051
Journal volume & issue
Vol. 2016

Abstract

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The goal of this paper was to investigate the antifungal activity of Enamel layers deposited on titanium substrate (Ti-Enamel) and Enamel layers deposited on titanium substrate previously coated with a vinyl polydimethylsiloxane layer (Ti-PDMS-Enamel). The physicochemical properties were also investigated. The Candida albicans biofilm development on the obtained layers was examined after 24 h, 48 h, and 72 h by confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM) after ethidium bromide staining. A significant inhibition of the fungal adherence and biofilm development was observed on Ti-Enamel layers. The antifungal results demonstrated that the use of new Ti-Enamel composite layers could represent a promising perspective for the prevention of fungal biofilms associated implant infections.