Topical treatment of psoriasis: questionnaire results on topical therapy as long-term continuous treatment and use on specific body sites

Abstract

Background Currently, no formalized international consensus guidelines exist to direct optimal topical treatment including long-term treatment. Objective In this survey, we aim to examine if and which topicals are used in clinical practice in long-term continuous treatment of psoriasis and how topicals are used in treating specific sites of the body. Methods A questionnaire was distributed electronically to dermatologists from the International Psoriasis Council (IPC) representing 26 countries. Results The top three topicals used across all severities of disease were topical corticosteroids, vitamin D analogs, and potent topical corticosteroids in combination with vitamin D analogs. On locations where the skin is thin, flexural and genital psoriasis, lower potency topical corticosteroids were used, whereas on other sites, in particular in palmoplantar psoriasis, superpotent topical corticosteroids and combination vitamin D analogs/corticosteroids were used. Conclusions It is relevant to optimize localized therapy for all severities of psoriasis reconciling disease activity (stable vs. unstable disease), localization of the lesions and the individual patient and his/her perspectives on disease control. Topical therapies are valuable treatments for classical mild disease and may have a position in some patients with more severe manifestations.

Keywords

• psoriasis
• topical therapy
• topical corticosteroids
• body surface area