Nature Communications (Apr 2019)

Regioselective radical α-borylation of α,β-unsaturated carbonyl compounds for direct synthesis of α-borylcarbonyl molecules

  • Shi-Chao Ren,
  • Feng-Lian Zhang,
  • Ai-Qing Xu,
  • Yinuo Yang,
  • Min Zheng,
  • Xiaoguo Zhou,
  • Yao Fu,
  • Yi-Feng Wang

DOI
https://doi.org/10.1038/s41467-019-09825-3
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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α-Borylcarbonyl compounds are versatile synthons in organic synthesis, however their preparation is often tedious. Here, the authors report a regioselective radical α-borylation of α,β-unsaturated carbonyl compounds to afford α-borylcarbonyl molecules with high selectivity and functional group compatibility.