Nature Communications (Feb 2023)

Nickel-catalyzed divergent Mizoroki–Heck reaction of 1,3-dienes

  • Wei-Song Zhang,
  • Ding-Wei Ji,
  • Ying Li,
  • Xiang-Xin Zhang,
  • Yong-Kang Mei,
  • Bing-Zhi Chen,
  • Qing-An Chen

DOI
https://doi.org/10.1038/s41467-023-36237-1
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 10

Abstract

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Developing efficient strategies to realize divergent arylation of dienes has been a longstanding synthetic challenge. Herein, a nickel-catalyzed divergent Mizoroki–Heck reaction of 1,3-dienes has been demonstrated through the modification of ligands and additives.