Nature Communications (Mar 2020)
Metagenome-wide association of gut microbiome features for schizophrenia
- Feng Zhu,
- Yanmei Ju,
- Wei Wang,
- Qi Wang,
- Ruijin Guo,
- Qingyan Ma,
- Qiang Sun,
- Yajuan Fan,
- Yuying Xie,
- Zai Yang,
- Zhuye Jie,
- Binbin Zhao,
- Liang Xiao,
- Lin Yang,
- Tao Zhang,
- Junqin Feng,
- Liyang Guo,
- Xiaoyan He,
- Yunchun Chen,
- Ce Chen,
- Chengge Gao,
- Xun Xu,
- Huanming Yang,
- Jian Wang,
- Yonghui Dang,
- Lise Madsen,
- Susanne Brix,
- Karsten Kristiansen,
- Huijue Jia,
- Xiancang Ma
Affiliations
- Feng Zhu
- Center for Translational Medicine, The First Affiliated Hospital of Xi’an Jiaotong University
- Yanmei Ju
- BGI-Shenzhen
- Wei Wang
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Qi Wang
- BGI-Shenzhen
- Ruijin Guo
- BGI-Shenzhen
- Qingyan Ma
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Qiang Sun
- BGI-Shenzhen
- Yajuan Fan
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Yuying Xie
- Department of Statistics and Probability, Michigan State University
- Zai Yang
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Zhuye Jie
- BGI-Shenzhen
- Binbin Zhao
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Liang Xiao
- BGI-Shenzhen
- Lin Yang
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Tao Zhang
- BGI-Shenzhen
- Junqin Feng
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Liyang Guo
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Xiaoyan He
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Yunchun Chen
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Ce Chen
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Chengge Gao
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- Xun Xu
- BGI-Shenzhen
- Huanming Yang
- BGI-Shenzhen
- Jian Wang
- BGI-Shenzhen
- Yonghui Dang
- School of Forensic Medicine, Xi’an Jiaotong University
- Lise Madsen
- BGI-Shenzhen
- Susanne Brix
- BGI-Shenzhen
- Karsten Kristiansen
- BGI-Shenzhen
- Huijue Jia
- BGI-Shenzhen
- Xiancang Ma
- Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University
- DOI
- https://doi.org/10.1038/s41467-020-15457-9
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 10
Abstract
Gut microbiome has been linked to neurogenerative diseases. Here, the authors present a metagenome-wide association study of schizophrenia (SZ) in human cohorts and identify SZ-associated specific gut-brain functional modules and pathways including SCFAs and neurotransmitters.