Nature Communications (2020-03-01)

Metagenome-wide association of gut microbiome features for schizophrenia

  • Feng Zhu,
  • Yanmei Ju,
  • Wei Wang,
  • Qi Wang,
  • Ruijin Guo,
  • Qingyan Ma,
  • Qiang Sun,
  • Yajuan Fan,
  • Yuying Xie,
  • Zai Yang,
  • Zhuye Jie,
  • Binbin Zhao,
  • Liang Xiao,
  • Lin Yang,
  • Tao Zhang,
  • Junqin Feng,
  • Liyang Guo,
  • Xiaoyan He,
  • Yunchun Chen,
  • Ce Chen,
  • Chengge Gao,
  • Xun Xu,
  • Huanming Yang,
  • Jian Wang,
  • Yonghui Dang,
  • Lise Madsen,
  • Susanne Brix,
  • Karsten Kristiansen,
  • Huijue Jia,
  • Xiancang Ma

DOI
https://doi.org/10.1038/s41467-020-15457-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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Gut microbiome has been linked to neurogenerative diseases. Here, the authors present a metagenome-wide association study of schizophrenia (SZ) in human cohorts and identify SZ-associated specific gut-brain functional modules and pathways including SCFAs and neurotransmitters.