BMC Infectious Diseases (Feb 2021)

Case series of acute appendicitis association with SARS-CoV-2 infection

  • Charlsea Prichard,
  • Matthew Canning,
  • Kindra McWilliam-Ross,
  • John Birbari,
  • William Parker,
  • Lori Wasson,
  • John W. Hollingsworth

DOI
https://doi.org/10.1186/s12879-021-05909-y
Journal volume & issue
Vol. 21, no. 1
pp. 1 – 4

Abstract

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Abstract Background Describe the indications for surgical interventions in asymptomatic patients with SARS-CoV-2. We are unaware of previous reports of an association between SARS-CoV-2 and acute appendicitis. Methods We performed a single institution retrospective review of SARS-CoV-2 pre-procedure testing and indications for surgical intervention. Statistical comparisons were performed using Chi Square analysis or two-tailed Student T test. Results We report a high prevalence of SARS-CoV-2 in both all testing and pre-procedure testing during the enrollment period. We observe a high prevalence of acute appendicitis among patients identified to be SARS-CoV-2 positive during pre-procedure testing and without recognized symptoms of COVID19. Conclusion We report a previously unrecognized association between SARS-CoV-2 and acute appendicitis.

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