Journal of Investigative Medicine High Impact Case Reports (Jun 2024)

Delayed Presentation of a Post-infarction Ventricular Septal Rupture

  • Omair Ahmed MD,
  • Harjinder Singh MD,
  • Sakshi Bai MD,
  • Diva Maraj MD,
  • Muhammad Ahmad Qureshi MD,
  • Elise Hawes ACS, RDCS,
  • Chidamber Alamelumangapuram MD,
  • Hussein Othman MD

DOI
https://doi.org/10.1177/23247096241262514
Journal volume & issue
Vol. 12

Abstract

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Ventricular septal rupture, a formidable complication of acute myocardial infarction (AMI), is linked to significant morbidity and mortality. The clinical manifestation typically involves pronounced hemodynamic compromise necessitating prompt surgical intervention. This report outlines the case of a 60-year-old male presenting with acute heart failure 3 weeks post a presumed AMI. On evaluation, a substantial ventricular septal defect with left-to-right shunt was observed. The patient, although hemodynamically stable with mild symptoms, underwent surgical closure of the defect and coronary artery bypass graft for multivessel coronary artery disease. This case contributes to the literature on the delayed presentation of post-myocardial infarction (MI) ventricular septal rupture, a scenario deviating from the anticipated severe hemodynamic instability given the timing of the MI and the extent of the septal defect.