Morbidity and mortality of sickle cell disease patients is unaffected by splenectomy: evidence from three decades of follow-up in a high-income setting

• Valeria Maria Pinto,
• Barbara Gianesin,
• Frédéric B. Piel,
• Filomena Longo,
• Paolo Rigano,
• Alessandra Quota,
• Vincenzo Spadola,
• Giovanna Graziadei,
• Filippo Mazzi,
• Maria Domenica Cappellini,
• Aurelio Maggio,
• Antonio Piga,
• Lucia De Franceschi,
• Gian Luca Forni

Affiliations

Valeria Maria Pinto

Center for Microcythemia, Congenital Anemia and Iron Dysmetabolism, Galliera Hospital, Genoa

Barbara Gianesin

ForAnemia Foundation, Genoa

Frédéric B. Piel

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London

Filomena Longo

Reference Centre for Hemoglobinopathies, AOU San Luigi Gonzaga Hospital, Orbassano

Paolo Rigano

Campus of Haematology Franco and Piera Cutino, AOOR Villa Sofia-V. Cervello, Palermo

Alessandra Quota

Thalassemia Unit, P.O. Vittorio Emanuele III, Gela, Caltanissetta Italy

Vincenzo Spadola

Thalassemia Center, P.O. Giovanni Paolo II, Ragusa

Giovanna Graziadei

Department of Medicine and Medical Specialities, IRCCS Ca' Granda Foundation, Maggiore Policlinico Hospital, Milan

Filippo Mazzi

Department of Medicine, University of Verona and AOUI Verona, Policlinico GB Rossi, Verona

Maria Domenica Cappellini

Department of Medicine and Medical Specialities, IRCCS Ca' Granda Foundation, Maggiore Policlinico Hospital, Milan

Aurelio Maggio

Campus of Haematology Franco and Piera Cutino, AOOR Villa Sofia-V. Cervello, Palermo

Antonio Piga

Department of Clinical and Biological Sciences, University of Turin

Lucia De Franceschi

Department of Medicine, University of Verona and AOUI Verona, Policlinico GB Rossi, Verona

Gian Luca Forni

Center for Microcythemia, Congenital Anemia and Iron Dysmetabolism, Galliera Hospital, Genoa