Endothelial Paracrine Action

Abstract

Some endothelial-derived compounds are able to cross the membrane and regulate the function of other nearby cells. The coronary arteries release endothelial factors and as such mediate paracrine action both on myocardiocytes and smooth muscle cells.Among the endothelial vasoactive substances released from the coronary arteries are Endothelial Derived Relaxing Factor (EDRF), Endothelial Derived Hyperpolarizing Factors (EDHFs), prostaglandins and endothelines 1,2,3 (ET-1, ET-2, ET-3). [...]