Nature Communications (Mar 2023)

Development of the oral resistome during the first decade of life

  • Smitha Sukumar,
  • Fang Wang,
  • Carra A. Simpson,
  • Cali E. Willet,
  • Tracy Chew,
  • Toby E. Hughes,
  • Michelle R. Bockmann,
  • Rosemarie Sadsad,
  • F. Elizabeth Martin,
  • Henry W. Lydecker,
  • Gina V. Browne,
  • Kylie M. Davis,
  • Minh Bui,
  • Elena Martinez,
  • Christina J. Adler

DOI
https://doi.org/10.1038/s41467-023-36781-w
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 14

Abstract

Read online

Here, the authors provide a longitudinal genetic surveillance of the antimicrobial resistance potential of the human oral microbiome in the first decade of life, revealing a dynamic environment altered by tooth decay with the increasing potential to mobilize genes as children grow.