The effect of metformin on some liver function tests in type 2 diabetic patients

Abstract

Objectives: To study the effect of metformin on serum glucose and some liver function tests including serum alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and bilirubin in type 2 diabetic patients. Design: Case-control study. Setting: The study was carried out in Al-Waffa centre for diabetes in Mosul, during the period from March 2004 to December 2004. Participants: Fifty type 2 diabetic patients treated with metformin were included. In addition, two control groups were used, 50 nontreated diabetic patients and 50 apparently healthy subjects. Results: Serum glucose in metformin treated diabetics -was lower (P