Metastatic renal cell carcinoma in an olfactory meningioma

Abstract

We report a case of renal cell carcinoma metastasing to an intracranial meningioma which has only been reported in eleven previous cases. A 55 year old man had previously undergone radical nephrectomy and developed pulmonary and gluteal metastasis in the following years, requiring pulmonectomy and surgical resection with combination of chemo and radiotherapy. As neurological symptoms developed, cranial MRI confirmed tumor within the anterior cranial fossa. Pathology confirmed the presence of metastatic renal cell carcinoma nidus with a surrounding meningioma. Positive history of extracranial cancer, rapid onset of new neurological signs or deteriorations, atypical radiological findings should raise the suspicion of potential metastases.

Keywords

• Olfactory meningioma
• Tumor-to-tumor metastasis
• Renal cell carcinoma