Fluorescent-Nanoparticle-Impregnated Nanocomposite Polymeric Gels for Biosensing and Drug Delivery Applications
Kumaraswamy Gandla,
K. Praveen Kumar,
P. Rajasulochana,
Manoj Shrawan Charde,
Ritesh Rana,
Laliteshwar Pratap Singh,
M. Akiful Haque,
Vasudha Bakshi,
Falak A. Siddiqui,
Sharuk L. Khan,
S. Ganguly
Affiliations
Kumaraswamy Gandla
Department of Pharmaceutical Analysis, Chaitanya (Deemed to be University), Hyderabad 500075, India
K. Praveen Kumar
Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Government of NCT of Delhi, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi 110017, India
P. Rajasulochana
Department of Microbiology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Kanchipuram 602105, India
Manoj Shrawan Charde
Department of Pharmaceutical Chemistry, Government College of Pharmacy, Karad 415124, India
Ritesh Rana
Department of Pharmaceutics, Himachal Institute of Pharmaceutical Education and Research (HIPER), Hamirpur 177033, India
Laliteshwar Pratap Singh
Department of Pharmaceutical Chemistry, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Rohtas 821305, India
M. Akiful Haque
Department of Pharmaceutical Analysis, School of Pharmacy, Anurag University, Hyderabad 500088, India
Vasudha Bakshi
Department of Pharmaceutics, School of Pharmacy, Anurag University, Hyderabad 500088, India
Falak A. Siddiqui
Department of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa 413520, India
Sharuk L. Khan
Department of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa 413520, India
S. Ganguly
Bar-Ilan Institute for Nanotechnology and Advanced Materials, Ramat Gan 5290002, Israel
Nanocomposite polymeric gels infused with fluorescent nanoparticles have surfaced as a propitious category of substances for biomedical purposes owing to their exceptional characteristics. The aforementioned materials possess a blend of desirable characteristics, including biocompatibility, biodegradability, drug encapsulation, controlled release capabilities, and optical properties that are conducive to imaging and tracking. This paper presents a comprehensive analysis of the synthesis and characterization of fluorescent-nanoparticle-impregnated nanocomposite polymeric gels, as well as their biomedical applications, such as drug delivery, imaging, and tissue engineering. In this discourse, we deliberate upon the merits and obstacles linked to these substances, encompassing biocompatibility, drug encapsulation, optical characteristics, and scalability. The present study aims to provide an overall evaluation of the potential of fluorescent-nanoparticle-impregnated nanocomposite polymeric gels for biomedical applications. Additionally, emerging trends and future directions for research in this area are highlighted.
