Analgesic Effect of a Kind of Herbal Medicine, Compared to Ibuprofen on Post-Endodontic Pain: A Randomized Clinical Trial Study

Abstract

Background: Pain management has always been a challenge in dentistry and especially after endodontic treatments. Hence, this study aimed to evaluate the analgesic effect of an herbal medication containing ginger and pineapple extract, curcumin, and bromelain, called Anaheal Plus, after endodontic treatment, compared to Ibuprofen.Materials and Methods: In this clinical trial study, 78 patients were randomly selected and divided into two groups. In group A, patients were asked to take 400mg Ibuprofen, whereas patients in group B,took Anaheal Plus before treatment. Pain intensity values were assessed and recorded using VAS scores. Pain was evaluated prior to endodontic treatment, as well as 6, 12- and 24-hours post-treatment. Mann-Whitney, Chi-square, Repeated measure ANOVA and Friedman tests were also applied to analyze the data.Results: The mean pain scores in groups A and B were 6.46±2.71 and 5.79±2.57 before treatment, 2.95±2.59 and 2.67±2.69 six hours after treatment, 1.49 ± 1.22 and 1.38± 0.79 12 hours after treatment, and 0.65± 0.31and 0.60± 0.28 24 hours after treatment, respectively. Statistical analysis showed no significant difference between Ibuprofen and Anaheal Plus groups in terms of the obtained pain scores during different time intervals.Conclusions: The findings of this study revealed that both Anaheal Plus and Ibuprofen had similar effects in pain alleviation for patients receiving endodontic treatment. Therefore, Anaheal Plus can be considered as an alternative analgesic drug in endodontic treatment due to its fewer side effects in comparison with Ibuprofen