IMMUNE STATE OF THE CHILDREN WITH BRONCHIAL ASTHMA FROM THE AMUR RIVER AND YAKUTIA REGIONS

M. V. Efimenko; M. I. Samsonova; E. N. Suprun; T. E. Burtseva; L. E. Nikolaeva; V. K. Kozlov

doi:10.15789/1563-0625-2013-4-383-387

Медицинская иммунология (Jul 2014)

IMMUNE STATE OF THE CHILDREN WITH BRONCHIAL ASTHMA FROM THE AMUR RIVER AND YAKUTIA REGIONS

M. V. Efimenko,
M. I. Samsonova,
E. N. Suprun,
T. E. Burtseva,
L. E. Nikolaeva,
V. K. Kozlov

Affiliations

M. V. Efimenko: Far Eastern State Medical University, Khabarovsk Branch, Far Eastern Center of Respiratory Physiology and Pathology, Russian Academy of Medical Sciences, Siberian Branch, Research Institute of Mother and Child Care, Khabarovsk
M. I. Samsonova: Yakut Research Centre of Complex Medical Problems, Russian Academy of Medical Sciences, Siberian Branch, Yakutsk
E. N. Suprun: Far Eastern State Medical University, Khabarovsk Branch, Far Eastern Center of Respiratory Physiology and Pathology, Russian Academy of Medical Sciences, Siberian Branch, Research Institute of Mother and Child Care, Khabarovsk
T. E. Burtseva: Yakut Research Centre of Complex Medical Problems, Russian Academy of Medical Sciences, Siberian Branch, Yakutsk
L. E. Nikolaeva: Yakut Research Centre of Complex Medical Problems, Russian Academy of Medical Sciences, Siberian Branch, Yakutsk
V. K. Kozlov: Far Eastern State Medical University, Khabarovsk Branch, Far Eastern Center of Respiratory Physiology and Pathology, Russian Academy of Medical Sciences, Siberian Branch, Research Institute of Mother and Child Care, Khabarovsk

DOI: https://doi.org/10.15789/1563-0625-2013-4-383-387
Journal volume & issue: Vol. 15, no. 4
pp. 383 – 387

Abstract

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Abstract. This work presents data on immune state of children with bronchial asthma living under environmental conditions of the Yakutia and Amur river regions. We examined immune functions of blood cells in 102 children with allergic diseases (bronchial asthma). Certain geographical and ecological conditions provide some specific change of immune system (immune deficiency) in the children with allergy. We have shown that the children with bronchial asthma exhibited immunological shifts in Th1/Th2 mechanism of immune responses, enhancement of humoral immune factors and deficiency of the phagocyte components.

Published in Медицинская иммунология

ISSN: 1563-0625 (Print); 2313-741X (Online)
Publisher: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
Country of publisher: Russian Federation
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy
Website: http://mimmun.ru/

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Abstract

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