Mean Platelet Volume and Coronary Artery Ectasia

Abstract

Abstract Objective: Coronary artery ectasia (CAE) are defined as the dilation of a segment of a coronary artery at least 1.5 times the adjacent segment. Several studies have shown the association between mean platelet volume (MPV) and cardiovascular diseases. But the results are different. For this reason, we aimed to investigate the association of MPV with CAE. Materials and Methods: 90 patients with normal coronary arteries and 70 patients with CAE were included. Routine blood and biochemical parameters were measured before the arteriography. Differences between groups for continuous variables were analyzed with t- test or Mann-Whitney U test. P values lt; 0.05 were considered significant. Results: Baseline patient demographics, including age and clinical risk factors, were similar between the groups. Compared to the control group, MPV levels were significantly lower in the CAE group (8.84 ± 1.71fL vs. 10.43 ± 1.34, p lt; 0.001). MPV level of lt; 9,5 fL showed sensitivity , specificity value of 95%, 80%; area under the curve= 0.943, 95% CI, 0.906–0.980) for the prediction of CAE. Conclusion: The present study suggests that MPV may decrease in patients with CAE.

Keywords

• angiography
• coronary aneurysms
• coronary artery disesas
• mean platelet volume.
• anjiyografi
• koroner arter hastalığı
• ortalama trombosit hacmi
• koroner anevrizma
• koroner arter hastalığı