CPT: Pharmacometrics & Systems Pharmacology (Aug 2019)

NONMEM Tutorial Part I: Description of Commands and Options, With Simple Examples of Population Analysis

  • Robert J. Bauer

DOI
https://doi.org/10.1002/psp4.12404
Journal volume & issue
Vol. 8, no. 8
pp. 525 – 537

Abstract

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In this tutorial, the various components of NONMEM will be described, and the basic steps of setting up NONMEM control stream files and data files will be demonstrated. Some basic concepts of nonlinear mixed effects modeling will be discussed, along with simple examples demonstrating how to use NONMEM to perform population analysis of clinical data.