Frontiers in Chemistry (Dec 2020)

Conductive Metal-Organic Frameworks for Amperometric Sensing of Paracetamol

  • Jing Wang,
  • Jing Wang,
  • Sen Liu,
  • Jiahuan Luo,
  • Shaogang Hou,
  • Haixiang Song,
  • Yongsheng Niu,
  • Chuanxiang Zhang

DOI
https://doi.org/10.3389/fchem.2020.594093
Journal volume & issue
Vol. 8

Abstract

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An electrochemical sensor for paracetamol is executed by using conductive MOF (NiCu-CAT), which is synthesized by 2, 3, 6, 7, 10, 11-hexahydroxytriphenylene (HHTP) ligand. The utility of this 2D NiCu-CAT is measured by the detection of paracetamol, p-stacking within the MOF layers is essential to achieve high electrical conductivity, redox activity, and catalytic activity. In particular, NiCu-CAT demonstrated detection Limit of determination near 5μM for paracetamol through a wide concentration range (5–190 μM). The NiCu-CAT/GCE exhibits excellent reproducibility, stability, and interference for paracetamol.

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