Periodically Disturbing the Spatial Structure of Biofilms Can Affect the Production of an Essential Virulence Factor in
<i>Pseudomonas aeruginosa</i>

Rebecca J. Quinn; Ivana Barraza; Laura García-Diéguez; Camryn Pajon; Lauren E. Krausfeldt; Kerollos Ibrahim; Laura A. Enzinna; Morgan E. Thorn; Omar Tonsi Eldakar; Travis J. A. Craddock; Robert P. Smith

doi:10.1128/mSystems.00961-21

mSystems (Oct 2021)

Periodically Disturbing the Spatial Structure of Biofilms Can Affect the Production of an Essential Virulence Factor in <i>Pseudomonas aeruginosa</i>

Rebecca J. Quinn,
Ivana Barraza,
Laura García-Diéguez,
Camryn Pajon,
Lauren E. Krausfeldt,
Kerollos Ibrahim,
Laura A. Enzinna,
Morgan E. Thorn,
Omar Tonsi Eldakar,
Travis J. A. Craddock,
Robert P. Smith

Affiliations

Rebecca J. Quinn: Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Ivana Barraza: Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Laura García-Diéguez: Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Camryn Pajon: Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Lauren E. Krausfeldt: ORCiD; Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Kerollos Ibrahim: Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Laura A. Enzinna: Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Morgan E. Thorn: Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Omar Tonsi Eldakar: Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA
Travis J. A. Craddock: Clinical Systems Biology Group, Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, Florida, USA
Robert P. Smith: ORCiD; Department of Biological Sciences, Halmos College of Arts and Science, Nova Southeastern University, Fort Lauderdale, Florida, USA

DOI: https://doi.org/10.1128/mSystems.00961-21
Journal volume & issue: Vol. 6, no. 5

Abstract

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Virulence factors are required to cause infections. Previous work has shown that the spatial organization of a population, such as a biofilm, can increase the production of some virulence factors, including pyoverdine, which is produced by Pseudomonas aeruginosa

Published in mSystems

ISSN: 2379-5077 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msystems

About the journal