Dementia and Geriatric Cognitive Disorders Extra (Mar 2012)

A Validation Study of the Japanese Version of the Addenbrooke’s Cognitive Examination-Revised

  • Kelssy Hitomi dos Santos Kawata,
  • Ryusaku Hashimoto,
  • Yoshiyuki Nishio,
  • Atsuko Hayashi,
  • Nanayo Ogawa,
  • Shigenori Kanno,
  • Kotaro Hiraoka,
  • Kayoko Yokoi,
  • Osamu Iizuka,
  • Etsuro Mori

DOI
https://doi.org/10.1159/000336909
Journal volume & issue
Vol. 2, no. 1
pp. 29 – 37

Abstract

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The aim of this study was to validate the Japanese version of the Addenbrooke’s Cognitive Examination-Revised (ACE-R) [Mori: Japanese Edition of Hodges JR’s Cognitive Assessment for Clinicians, 2010] designed to detect dementia, and to compare its diagnostic accuracy with that of the Mini-Mental State Examination. The ACE-R was administered to 85 healthy individuals and 126 patients with dementia. The reliability assessment revealed a strong correlation in both groups. The internal consistency was excellent (α-coefficient = 0.88). Correlation with the Clinical Dementia Rating sum of boxes score was significant (rs = –0.61, p < 0.001). The area under the curve was 0.98 for the ACE-R and 0.96 for the Mini-Mental State Examination. The cut-off score of 80 showed a sensitivity of 94% and a specificity of 94%. Like the original ACE-R and the versions designed for other languages, the Japanese version of the ACE-R is a reliable and valid test for the detection of dementia.

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