Characterization data of gilthead sea bream (Sparus aurata) IGF-I receptors (IGF-IRa/Rb)
Emilio J. Vélez,
Sheida Azizi,
Cristina Salmerón,
Shu Jin Chan,
Mohammad Ali Nematollahi,
Bagher Mojazi Amiri,
Isabel Navarro,
Encarnación Capilla,
Joaquim Gutiérrez
Affiliations
Emilio J. Vélez
Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain
Sheida Azizi
Department of Fisheries Sciences, Faculty of Natural Resources, University of Tehran, Karaj, Iran; Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, 08028 Barcelona, Spain. Visitor PhD student
Cristina Salmerón
Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain
Shu Jin Chan
Department of Biochemistry and Molecular Biology and Department of Medicine and the Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA
Mohammad Ali Nematollahi
Department of Fisheries Sciences, Faculty of Natural Resources, University of Tehran, Karaj, Iran
Bagher Mojazi Amiri
Department of Fisheries Sciences, Faculty of Natural Resources, University of Tehran, Karaj, Iran
Isabel Navarro
Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain
Encarnación Capilla
Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain
Joaquim Gutiérrez
Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain; Correspondence to: Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain. Tel.: +34 934021532; fax: +34 934110358.
In this data article we describe the coding sequence of two IGF-IR paralogues (IGF-IRa and IGF-IRb) obtained from gilthead sea bream embryos. The putative protein architecture (domains and other important motifs) was determined and, amino acid sequences alignment and phylogenetic analysis of both receptors together with IGF-IR orthologues from different vertebrates was performed. Additionally, a semi-quantitative conventional PCR was done to analyze the mRNA expression of both receptors in different tissues of gilthead sea bream. These data will assist in further physiological studies in this species. In this sense, the expression of both receptors during ontogeny in muscle as well as the differential effects of IGF-I and IGF-II on their regulation during in vitro myogenesis has been recently studied (doi: 10.1016/j.ygcen.2015.11.011; [1]). Keywords: IGF-I receptors, Gilthead sea bream
