Bronchiectasis: A retrospective study of clinical and aetiological investigation in a general respiratory department

Revista Portuguesa de Pneumologia (English Edition). 2015;21(1):5-10

 

Journal Homepage

Journal Title: Revista Portuguesa de Pneumologia (English Edition)

ISSN: 2173-5115 (Online)

Publisher: Elsevier

Society/Institution: Sociedade Portuguesa de Pneumologia

LCC Subject Category: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system

Country of publisher: Netherlands

Language of fulltext: English

Full-text formats available: PDF, HTML

 

AUTHORS

A. Amorim (Faculty of Medicine, University of Porto, Portugal; Pneumology, Centro Hospitalar de S. João, EPE, Porto, Portugal; Corresponding author.)
J. Bento (Pneumology, Centro Hospitalar de S. João, EPE, Porto, Portugal)
A.P. Vaz (Pneumology, Centro Hospitalar de S. João, EPE, Porto, Portugal)
I. Gomes (Pneumology, Centro Hospitalar de S. João, EPE, Porto, Portugal)
J. de Gracia (Faculty of Medicine, Autonomous University of Barcelona, Spain; Pneumology, CIBER Enfermedades Respiratorias (CIBERES) Hospital Vall d’Hebron, Barcelona, Spain)
V. Hespanhol (Faculty of Medicine, University of Porto, Portugal; Pneumology, Centro Hospitalar de S. João, EPE, Porto, Portugal)
A. Marques (Faculty of Medicine, University of Porto, Portugal; Pneumology, Centro Hospitalar de S. João, EPE, Porto, Portugal)

EDITORIAL INFORMATION

Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 8 weeks

 

Abstract | Full Text

Background: Bronchiectasis can result from many diseases, which makes the aetiological investigation a complex process demanding special resources and experience. The aetiological diagnosis has been proven to be useful for the therapeutic approach. Objective: Evaluate how accurately and extensive the clinical and aetiological research was for adult bronchiectasis patients in pulmonology outpatient service which were not following a pre-existing protocol. Methods: We retrospectively reviewed the records of 202 adult patients with bronchiectasis, including the examinations performed to explain the aetiology. Results: The mean age of the patients was 54 ± 15 years, there was a predominance of female (63.9%) and non-smoker (70%) patients. Functional evaluation showed a mild airway obstruction.The sputum microbiological examination was available for 168 patients (43.1% had 3 or more sputum examinations during one year). Immunoglobulins and α1-antitrypsin were measured in around 50% of the patients. The sweat test and the CF genotyping test were performed in 18% and 17% of the patients, respectively.The most commonly identified cause was post-infectious (30.3%), mostly tuberculosis (27.2%). No definitive aetiological diagnosis was established in 57.4% of the patients. We achieved a lower aetiological diagnosis if we compare our series with studies in which a diagnostic algorithm was applied prospectively. Conclusions: The general characteristics of our patients were similar with other series. Detailed investigation of bronchiectasis is not a standard practice in our outpatient service. These results suggest that the use of a predefined protocol, based on current guidelines, could improve the assessment of these patients and facilitate the achievement of a definitive aetiology. Keywords: Adult, Bronchiectasis, Clinical investigation, Aetiology, Respiratory service