Limited effects of m6A modification on mRNA partitioning into stress granules

Anthony Khong; Tyler Matheny; Thao Ngoc Huynh; Vincent Babl; Roy Parker

doi:10.1038/s41467-022-31358-5

Nature Communications (Jun 2022)

Limited effects of m6A modification on mRNA partitioning into stress granules

Anthony Khong,
Tyler Matheny,
Thao Ngoc Huynh,
Vincent Babl,
Roy Parker

Affiliations

Anthony Khong: Department of Biochemistry, University of Colorado
Tyler Matheny: Department of Biochemistry, University of Colorado
Thao Ngoc Huynh: Department of Biochemistry, University of Colorado
Vincent Babl: Department of Biochemistry, University of Colorado
Roy Parker: Department of Biochemistry, University of Colorado

DOI: https://doi.org/10.1038/s41467-022-31358-5
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 10

Abstract

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Recent studies proposed that m6A modification in mammalian mRNAs increases their recruitment to stress granule. However, here the authors observed that m6A modification has a limited effect on mRNA entry into stress granules.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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