Бюллетень сибирской медицины (Oct 2011)

Experimental histochrome's effect on the renal excretory function

  • O. S. Talalayeva,
  • A. Yu. Zharikov,
  • S. A. Fedoreyev,
  • Ya. F. Zverev,
  • V. M. Bryukhanov,
  • N. P. Mishchenko,
  • V. V. Lampatov

DOI
https://doi.org/10.20538/1682-0363-2011-5-101-105
Journal volume & issue
Vol. 10, no. 5
pp. 101 – 105

Abstract

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The aim of present investigation was to establish possible histochrome's effect on the renal excretory function. During 10 days was being administrated histochrome by subcutaneous injections in dose 10 mg/kg. Every 2 days was being detected daily renal excretions of water, creatinin, sodium and potassium. Long-term histochrome's administration was followed by a fivefold increasing of water excretion and comparable amplification of creatinin. Sodium's and potassium's excretions were increasing to a lesser degree. The revealed histochrome's diuretic effect qualitatively reminds action of diuretic plants, but quantitatively it was compared with thiazid's one.

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