Skeletal reorganization divergence of N-sulfonyl ynamides

Linwei Zeng; Yuxin Lin; Jiaming Li; Hironao Sajiki; Hujun Xie; Sunliang Cui

doi:10.1038/s41467-020-19467-5

Nature Communications (Nov 2020)

Skeletal reorganization divergence of N-sulfonyl ynamides

Linwei Zeng,
Yuxin Lin,
Jiaming Li,
Hironao Sajiki,
Hujun Xie,
Sunliang Cui

Affiliations

Linwei Zeng: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University
Yuxin Lin: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University
Jiaming Li: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University
Hironao Sajiki: Laboratory of Organic Chemistry, Gifu Pharmaceutical University
Hujun Xie: School of Food Science and Biotechnology, Zhejiang Gongshang University
Sunliang Cui: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University

DOI: https://doi.org/10.1038/s41467-020-19467-5
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 10

Abstract

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Skeletal reorganizations are intriguing processes in chemical synthesis due to their mechanism, atom-economy and synthetic versatility. Herein, the authors describe a divergent skeletal reorganization of N-sulfonyl ynamides to thiete sulfones and propargyl sulfonamides.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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