Nature Communications (Mar 2021)

Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs

  • Henry Gerdes,
  • Pedro Casado,
  • Arran Dokal,
  • Maruan Hijazi,
  • Nosheen Akhtar,
  • Ruth Osuntola,
  • Vinothini Rajeeve,
  • Jude Fitzgibbon,
  • Jon Travers,
  • David Britton,
  • Shirin Khorsandi,
  • Pedro R. Cutillas

DOI
https://doi.org/10.1038/s41467-021-22170-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

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Artificial intelligence and machine learning promise to transform cancer therapies by accurately predicting the most appropriate drugs to treat individual patients. Here, the authors present an approach which uses omics data to produce ordered lists of drugs based on their effectiveness in decreasing cancer cell proliferation.