Iron-binding property of lactoferrin in the case of inflammation

Abstract

Lactoferrin (Lf) is a biologically important molecule, that accomplishes a number of useful functions in an organism. Lf can be situated in conditions associated with enrichment of reactive halogen species (asthma, infectious disease, heart-disease etс.). It was shown using spectrophotometric and fluorescence methods that HOCl and particularly HOBr lead to significant destruction of Trp residues and iron-binding capacity of Lf.

Keywords

• hocl
• hobr
• lactoferrin
• tryptophan
• iron binding property
• hocl
• hobr