A Brief Review Bio-Synthesized Silver Nanoparticles and Their Antimicrobial Potential

Abstract

The synthesis, applications, and antimicrobial investigation of Silver Nanoparticles (AgNPs) have been indicated in several studies. However, only few studies were published characterizing the features of biologically synthesized AgNPs. Silver also, it salts long been employed by the old civilizations without reporting sides effects on the human health. While, Ag NPs has been just recently produced and used in the industrial, agricultural and medical applications. Regarding pharmaceutical applications, AgNPs have been used as antimicrobial and antioxidants agent because of the generation of free radicals (- o2) and reactive oxygen species (ROS), which cell killing/inhibition. The small size of AgNPs is facilitating their diffusion into cell lead to cell wall rupture. However, the small sized-AgNPs are associated with their toxicity, the smaller size nanoparticles, and the more toxic ones. AgNPs toxicity also depends on the environment's pH and concentration, in addition to size. In addition to discussing their antibacterial action and toxicity, this study will cover the numerous AgNPs manufacturing techniques and uses.

Keywords

• Silver nanoparticles; Bio-synthesis; Applications; Antimicrobial activity; Toxicity.