Deep longitudinal multiomics profiling reveals two biological seasonal patterns in California

M. Reza Sailani; Ahmed A. Metwally; Wenyu Zhou; Sophia Miryam Schüssler-Fiorenza Rose; Sara Ahadi; Kevin Contrepois; Tejaswini Mishra; Martin Jinye Zhang; Łukasz Kidziński; Theodore J. Chu; Michael P. Snyder

doi:10.1038/s41467-020-18758-1

Nature Communications (Oct 2020)

Deep longitudinal multiomics profiling reveals two biological seasonal patterns in California

M. Reza Sailani,
Ahmed A. Metwally,
Wenyu Zhou,
Sophia Miryam Schüssler-Fiorenza Rose,
Sara Ahadi,
Kevin Contrepois,
Tejaswini Mishra,
Martin Jinye Zhang,
Łukasz Kidziński,
Theodore J. Chu,
Michael P. Snyder

Affiliations

M. Reza Sailani: Department of Genetics, Stanford University
Ahmed A. Metwally: Department of Genetics, Stanford University
Wenyu Zhou: Department of Genetics, Stanford University
Sophia Miryam Schüssler-Fiorenza Rose: Department of Genetics, Stanford University
Sara Ahadi: Department of Genetics, Stanford University
Kevin Contrepois: Department of Genetics, Stanford University
Tejaswini Mishra: Department of Genetics, Stanford University
Martin Jinye Zhang: Department of Electrical Engineering, Stanford University
Łukasz Kidziński: Department of Bioengineering, Stanford University
Theodore J. Chu: Department of Pediatrics, Division of Allergy and Immunology, Stanford University
Michael P. Snyder: Department of Genetics, Stanford University

DOI: https://doi.org/10.1038/s41467-020-18758-1
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 12

Abstract

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Seasonal patterns of molecular markers in humans have not been extensively studied. Here, the authors combine host components (transcriptome, metabolome, proteome, immunome, clinical lab tests) and microbiome to profile 105 individuals, identifying over 1000 markers in two major seasonal patterns.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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