Risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation in patients with stage I non‐small cell lung cancer: A bicentric retrospective study

Abstract

Abstract Objectives This study aimed to identify the risk factors for lung parenchyma hemorrhage and hemoptysis during computed tomography‐guided microwave ablation (MWA) in patients with stage I non‐small cell lung cancer (NSCLC). Methods A total of 417 patients from two medical centers were included, of whom 353 were from center 1 and 64 were from center 2. The risk factors for lung parenchyma hemorrhage and hemoptysis were selected by univariable and multivariable logistic analyses in the center 1 dataset. The selected risk factors were validated in the center 2 dataset. Results The risk factors for lung parenchyma hemorrhage during MWA were focal blood supplies (odds ratio [OR], 2.602; 95% confidence interval [CI], 1.609–4.210; p 25 mm (OR, 4.494; 95% CI, 1.833–11.018; p = 0.001), and traversing vessels in the track of ablation (OR, 5.402; 95% CI, 2.269–12.865; p 25 mm, and traversing vessels in the track of ablation were independent risk factors for hemoptysis during MWA.

Keywords

• complication
• computed tomography
• hemorrhage
• microwave ablation
• pulmonary malignancy