Structural Connectivity Reorganization Based on DTI after Cingulotomy in Obsessive–Compulsive Disorder

Abstract

Bilateral cingulotomy is a procedure applied to patients with obsessive–compulsive disorder (OCD). This report presents the structural changes occurring within the forceps minor and arcuate fascicles nerve fibers after a successful bilateral anterior cingulotomy in the patient with refractory OCD. Cingulotomy mainly affects the values of FA, MD, and ADC in the treatment of the examined nerve bundles. This structural reorganization coexists with a good clinical effect. However, it is necessary to expand the study group and to investigate the correlation between the parameters of diffusion and anisotropy and the patient’s clinical condition (Y-BOCS scale).

Keywords

• diffusion-tensor imaging
• tractography
• arcuate fasciculus
• cingulotomy
• forceps minor
• obsessive–compulsive disorder