Histological comparison between histoacryl and suturing to close lung wounds in dogs

Abstract

The study was designed to know if there is any histological difference between using suturing and histoacryl (n-2-butyl-cyanoacrylate) for closing small parenchymal lung wounds in dogs. Twelve adult dogs were used in this study. The experimental animals were divided into two equal groups of six animals each. After induction of general anesthesia, a left intercostal thoracotomy was done, and a small incision of 2cm was made on the parenchymal lung tissue. Then, in the first group, the lung wound was closed by suturing, while in the second group, the wound was sealed by applying adhesive tissue glue. The histopathological samples were collected on the 15th and 30th days postoperatively. The histopathological changes in both groups were relatively similar, manifested by formation of granulation tissue, infiltration of inflammatory cells, congestion and thinking in the wall of blood vessels, hemorrhage, edema, atelectasis, and interstitial emphysema. In conclusion, we can use histoacryl as an effective adhesive tissue glue to close small lung wounds due to the absence of any relative histopathological differences between suturing and histoacryl for closing lung wounds.

Keywords

• thoracotomy
• lung wound closure
• tissue glue